I was a very efficient doctor. I would get rewarded with a lot more patients. By the end of my medical career, I had maybe 2,000 patients in my practice.

I wasn't sued out of medicine, I wasn't arbitrated out of the profession.

I always say 'Knocked Up' opened the doors, and 'Hangover' just burst it wide open. To this day, it's still surreal. And my wife's a doctor. All our friends are doctors - our close friends. And it's just that I have an odd job now. I think I'm like a doctor who had a detour, and I just have an odd job.

I never let on I was a comedian. I never acted out. It was really important to me, like, to not be Patch Adams. I was so super serious as a doctor, I would bark orders to my nurses. I was hard-core. I wanted to make sure I did my job right. I was perfectly trained to be a physician. You know, it wasn't a fluke. I worked hard at it.

I was so focused on advancing in my career that I didn't have enough emotional capacity for dating.

I absolutely have loved my career path and everything that I've done personally, but it was tough.

I never 'went Hollywood.' Perhaps some of my behavior was detrimental to my career, but I couldn't go the route of Hollywood parties.

Oh, my father's had a huge, immense impact on my career. I grew up on movie sets that he was working on, and it just become a part or was a part, was the only part of my life because I spent my whole childhood traveling and being on film sets.