I turned 65 last year, and each year I get more and more interested in human health. For most people it happens around age 50, but I've always been a slow learner. It's critical in terms of the cost of health care.

I've had a very unusual background in science - not the usual route of planning on being a scientist from age 3. I think my story shows that success is more about personal motivation and determination than it is about where you were born or what your economic status was.

In the past, geneticists have looked at so-called disease genes, but a lot of people have changes in their genes and don't get these diseases. There have to be other parts of physiology and genetics that compensate.

My early years were hardly a model of focus, discipline, and direction. No one who met me as a teenager could have imagined my going into research and making important discoveries. No one could have predicted the arc of my career.

I have a saying: There are no brave old people in finance. Because if you're brave, you mostly get destroyed in your 30s and 40s. If you make it to your 50s and 60s and you're still prospering, you have a very good sense of how to avoid problems and when to be conservative or aggressive with your investments.

Since I was an atheist for many years and came to believe in God through my studies in science, it frustrated me to see students and parents who viewed faith and science as enemies.

Obama came in really wanting to change things, but he hit a wall of corporate money, oil and coal money: when he tried to pass the Cap and Trade system of pharmaceutical money, when he tried to pass the Obamacare - which, of course, then got watered down into a much less effective, much less economical, program.

If I'm paying money to come to see you, you shouldn't look like everybody else in the crowd.