I turned 65 last year, and each year I get more and more interested in human health. For most people it happens around age 50, but I've always been a slow learner. It's critical in terms of the cost of health care.

I've had a very unusual background in science - not the usual route of planning on being a scientist from age 3. I think my story shows that success is more about personal motivation and determination than it is about where you were born or what your economic status was.

In the past, geneticists have looked at so-called disease genes, but a lot of people have changes in their genes and don't get these diseases. There have to be other parts of physiology and genetics that compensate.

My early years were hardly a model of focus, discipline, and direction. No one who met me as a teenager could have imagined my going into research and making important discoveries. No one could have predicted the arc of my career.

Much of Indian science seems intuitive and not bound by the rigid thinking of classical scientists.

I love technology, and I love science. It's just always all in the way you use it. So there's no - you can't really blame anything on the technology. It's just the way people use it, and it always has been.

We're losing track of the vastness of the potential for computer science. We really have to revive the beautiful intellectual joy of it, as opposed to the business potential.

I'm friends with James Cameron. We've spent time together over the years because he is a diver and explorer and in his heart of hearts a biologist. We run into each other at scientific conferences.