I turned 65 last year, and each year I get more and more interested in human health. For most people it happens around age 50, but I've always been a slow learner. It's critical in terms of the cost of health care.

I've had a very unusual background in science - not the usual route of planning on being a scientist from age 3. I think my story shows that success is more about personal motivation and determination than it is about where you were born or what your economic status was.

In the past, geneticists have looked at so-called disease genes, but a lot of people have changes in their genes and don't get these diseases. There have to be other parts of physiology and genetics that compensate.

My early years were hardly a model of focus, discipline, and direction. No one who met me as a teenager could have imagined my going into research and making important discoveries. No one could have predicted the arc of my career.

From the moment I turned 39, 40, I really turned a corner and became a person who really enjoys working out. When I don't get a chance to, I miss it. I also just recognized that it would give me career longevity if I kept myself in the best shape I could possibly be in.

At the core of 'Star Trek' is Gene Roddenberry's vision of the future. So much of science-fiction is about a dystopian society with human civilization having crumbled. He had an affirmative, shining, positive view of the future.

The entire Internet, as well as the types of devices represented by the desktop computer, the laptop computer, the iPhone, the iPod, and the iPad, are a continuing inescapable embarrassment to science fiction, and an object lesson in the fallibility of genre writers and their vaunted predictive abilities.

Not every time someone gets hit these days with a kick, they don't necessarily take a flat-back. Maybe less flat-backs add time to a career, but if they miss some of it, it just seems like you're done.