The goal of a private company is, first, zero to one: Get past the product-market fit; figure out whether people actually care about what you're trying to build and someone will pay you money for that. That's the zero to one problem.

None of us are going to fix governance; it may just be beyond repair. But you can fix capitalism. And the reason you can fix capitalism - It is inherently numerical, and as a result, it is inherently objective. It can be done objectively.

My first job was at a Burger King.

Your job as a smart investor is to separate the facts and the news from the fiction and the noise.

The evolution of sex is the hardest problem in evolutionary biology.

In the history of science, we often find that the study of some natural phenomenon has been the starting point in the development of a new branch of knowledge.

Indeed, scientific truth by consensus has had a uniformly bad history.

I think of 'data science' as a flag that was planted at the intersection of several different disciplines that have not always existed in the same place. Statistics, computer science, domain expertise, and what I usually call 'hacking,' though I don't mean the 'evil' kind of hacking.