I remember, when I was an up-and-coming comic, how annoyed I would be when the famous guys would show up and just take everyone's spots.

I guess it's a kind of a goal for any actor to be the lead of a movie. Not for ego reasons, but because it is creatively the biggest challenge.

As soon as I realized you could be funny as a job, that was the job I wanted.

I'm proud to say that I've never had a normal job. I started doing stand-up when I was in high school, purely as a measure to never get a proper job.

The United States cannot and should not discriminate on the basis of religion. The free exercise of religion is at the very heart of our constitutional guarantee for all persons of this country.

The Internet was appealing partly because it was something I could do in bed and feel like I was achieving something. I had an operation when I was 13 and ended up with complications, so I was in and out of the hospital. The bottom line is you can get through health challenges. It's part of why I was so driven.

A modern health and social care system has to be completely focussed on the needs of its users.

Exercise is really important to me - it's therapeutic. So if I'm ever feeling tense or stressed or like I'm about to have a meltdown, I'll put on my iPod and head to the gym or out on a bike ride along Lake Michigan with the girls.