The last thing you ever want to do is extend the period of frailty and disability and make people unhealthy for a longer time period. So lifespan extension in and of itself should not be the goal of medicine, nor should it be the goal of public health, nor should it be the goal of aging science.

Once you avoid the things that accelerate aging like smoking, obesity, excessive alcohol consumption, and excessive sun exposure, you've done about as much as you can to influence your aging process.

We have grown accustomed to the wonders of clean water, indoor plumbing, laser surgery, genetic engineering, artificial joints, replacement body parts, and the much longer lives that accompany them. Yet we should remember that the vast majority of humans ever born died before the age of 10 from an infectious disease.

Ageing is very rare. We only see it in humans and laboratory animals and in zoo animals and in our pets. Basically, organisms that are protected from the external world. Once you create that protection, you live long enough to see ageing.

Over the years, my relationship with God has changed my life for the better - it's grown me up, given me a sense of purpose, and grounded me in my identity.

I probably have a hidden issue, because before 'La Misma Luna' in 2007, I hated working with kids. But after that, I learned so much about how to handle a kid that I liked it. And then came 'Instructions Not Included,' and it was like, 'OK, now I think I've got it.' Life just kept bringing me projects with kids.

When I went to Sundance for 'Afternoon Delight,' I came back feeling like I wanted to take my experience that I learned from directing and bring that into a series.

Although I performed in high school, my first real experience with theater was performing with a student-run organization at Vanderbilt University called The Original Cast where I learned that I loved performing and especially loved theater people.