The last thing you ever want to do is extend the period of frailty and disability and make people unhealthy for a longer time period. So lifespan extension in and of itself should not be the goal of medicine, nor should it be the goal of public health, nor should it be the goal of aging science.

Once you avoid the things that accelerate aging like smoking, obesity, excessive alcohol consumption, and excessive sun exposure, you've done about as much as you can to influence your aging process.

We have grown accustomed to the wonders of clean water, indoor plumbing, laser surgery, genetic engineering, artificial joints, replacement body parts, and the much longer lives that accompany them. Yet we should remember that the vast majority of humans ever born died before the age of 10 from an infectious disease.

Ageing is very rare. We only see it in humans and laboratory animals and in zoo animals and in our pets. Basically, organisms that are protected from the external world. Once you create that protection, you live long enough to see ageing.

I'll exercise in spurts, usually inspired by a dress that I have to fit into. But once that gown is squeezed into, if I continue to exercise, I get sick or I pull my back. For some reason my body literally rejects exercise.

I have young kids. The fiscal burden that will be imposed on them is going to depend primarily on whether we tackle this looming problem in our health care system - with rising costs that don't seem, by the way, to be necessarily associated with higher quality. That is the key burden that they will face.

I used to be a health-care investor a long time ago in the public markets. One thing I learned that we tried to apply here is that investing in small molecules, trying to invest in the next treatment, there's an element of gambling to that.

Maybe it's every kid's dream to go into a pod and come out looking like Captain America. And you don't even have to exercise or lift weights! It's great!