Even though the show is called 'Childrens Hospital,' we don't use kids a lot. They always want a juice box or a fruit roll up or a nap.

I think there are a lot of really funny things in 'The Descendants,' but there're a lot of different tones in that movie, in the same way that 'Transparent' has a lot of different tones.

There's no way to play it cool when you meet Paul McCartney. You just start sweating; you trip over your words. Everyone kind of reverts back to being a 10-year-old girl. You can't help it. He's one of the only people on planet Earth that everyone knows who he is. Everyone.

My mom has this thing where if I'm doing anything doing dirty or crazy, she sniffs it out and yells at me. But the good thing is my mom doesn't have cable, and so much of the stuff I've done was on cable, so many times she'll miss it. I tend to gloss over the crazier things I shoot.

Edward Norton and I have known each other awhile. I just think he's the real deal, supremely talented and smart. He's got a great sense of humor.

How I've fed my kids over the years is by doing stand-up comedy in clubs.

The first Emmys I went to was in 1990 when the five nominees for best comedy were 'Designing Women,' 'Golden Girls,' 'Murphy Brown,' 'Cheers,' 'Wonder Years.' Three and a half were created by women.

You need more than a year to grow on somebody, and it's very intimate being invited into people's homes every day. Once that trust is built, then you're like that old friend. That's the sweet spot.