Especially working in infectious disease, it's very interesting because these infectious diseases, these agents, they evolve over time. So it's very much an arms race and understanding how each changes to protect itself and to continue. And so it's very much this puzzle-solving but with this great urgency and importance in what you find.

The process of discovery in my field is very incremental. But there are moments when you realize you know something about the world nobody else knows. That's extraordinarily exhilarating.

You get these moments of thrill. There you are, at 3:00 in the morning, and you know something about how we evolved that nobody else in the world knows. It's a thrill of discovery. You make this breakthrough, and you find something. It's this wonderful, wonderful scavenger hunt when you got to the end. It's just so great to be a scientist.

The great thing about America is I've never felt like an outsider. I'm just a different piece of the puzzle.

The whole London football scene is now financially more powerful and ambitious than ever before. That reflects the city's economic might and its multiculturalism. Now West Ham have a new , and Spurs and Chelsea will follow. And the London clubs have widened their areas of support.

I don't do too much outside of football during football season, because this is my job and I take it seriously. I don't do too much, don't really go out at all that much, don't eat out or anything, try to stay focused and stay to myself.

I was so fully involved in football and building a career that I didn't spend nearly enough time with my son when he was growing up.

If you're talking about English football very few teams play 4-4-2 now: it's either 4-4-1-1, 4-3-3 or 4-2-3-1, they are the three major systems played throughout the Premier League.