The willingness to be self-critical in England is much greater than the willingness to be self-critical in America.

You think it matters to the kids whether they're learning to play on a Steinway or a normal piano?

Part of me thinks that innovation, real innovation in health care delivery, needs to happen from the bottom to the top.

So, it's a very, you know - maybe we're wrong in - you know, we go around thinking the innovator is the person who's first to kind of conceive of something. And maybe the innovation process continues down the line to the second and the third and the fourth entrant into a field.

I'm not on a mission. I'm not a paragon of health for anybody. I'm not going to run a marathon or model for 'Men's Health' or go on bike rides with Lance Armstrong. I'm not. Trust me.

Antibiotics are a very serious public health problem for us, and it's getting worse. Resistant microbes outstrip new antibiotics. It's an ongoing problem. It's not like we can fix it, and it's over. We have to fight continued resistance with a continual pipeline of new antibiotics and continue with the perpetual challenge.

I have always stood up to protect women's access to safe and legal abortion, birth control and health care at Planned Parenthood.

No innovation in the past 200 years has done more to save lives and improve health than the sanitation revolution triggered by invention of the toilet. But it did not go far enough. It only reached one-third of the world.