Scientists have made extraordinary advances in understanding the brain and its disorders.

You become aware of an illness by understanding yourself and understanding the meaning that that illness has in your own life, symbolically and, more importantly, quite literally.

When public figures remain silent about depression, there is a cost to the rest of society. Silence contributes to the misperception that successful people do not get depressed, and it keeps the public from seeing that treatment allows many individuals to return to competitive professional lives.

Mania is as bad as it gets. If not treated, it will become worse, more frequent, and harder to treat.

If you live a life of make-believe, your life isn't worth anything until you do something that does challenge your reality. And to me, sailing the open ocean is a real challenge, because it's life or death.

Consciousness after death demonstrates the possibility of consciousness operating independently of the body.

I'm a trumpet player, so I always carry a pocket trumpet in case there's an opportunity to jam with the locals. I was in Guadeloupe last year filming 'Death in Paradise,' and I played all over the island and had the best time.

I guess I don't believe that death is the end.