Fundamental discoveries can and should be made in industry or academies, but to carry that knowledge forward and to develop a new drug to the market has to depend on the resources of industry.

The medicines of today are based upon thousands of years of knowledge accumulated from folklore, serendipity and scientific discovery. The new medicines of tomorrow will be based on the discoveries that are being made now, arising from basic research in laboratories around the world.

It is sometimes said that the major discoveries have already been made and that there is nothing important left to find. This attitude is altogether too pessimistic. There are plenty of ideas and plenty of things left to discover. The trick is to find the right path from one to the other.

At first, I was able to use a Bunsen burner attached to my mother's gas stove, but the use of the kitchen as a laboratory came to an abrupt end when a minor explosion involving hydrogen sulphide spattered the newly painted decor and changed the colour from blue to dirty green!