The purest case of an intelligence explosion would be an Artificial Intelligence rewriting its own source code. The key idea is that if you can improve intelligence even a little, the process accelerates. It's a tipping point. Like trying to balance a pen on one end - as soon as it tilts even a little, it quickly falls the rest of the way.

Anything that could give rise to smarter-than-human intelligence - in the form of Artificial Intelligence, brain-computer interfaces, or neuroscience-based human intelligence enhancement - wins hands down beyond contest as doing the most to change the world. Nothing else is even in the same league.

There's a popular concept of 'intelligence' as book smarts, like calculus or chess, as opposed to, say, social skills. So people say that 'it takes more than intelligence to succeed in human society.' But social skills reside in the brain, not the kidneys.

A burning itch to know is higher than a solemn vow to pursue truth. To feel the burning itch of curiosity requires both that you be ignorant, and that you desire to relinquish your ignorance.

The growth of technology is such that it is not possible today for a nuclear physicist to switch into medical physics without training. The field is now much more technical. More training is needed to do the job.

I draft on the computer. I have a really giant screen that attaches to my laptop, and then I have a humongous digital drawing tablet called a Cintiq. It sits at all different angles, and it's so big that it would take two people to move it.

It has been wild, you know? I started out just putting a song that I made out on the Internet without being sure if anyone was going to like it, and it took me on tour around the world with Justin Bieber. It's been amazing!

The internet was supposed to make this whole business of job searching rational and simple. You could post your resume and companies would search them and they'd find you. It doesn't seem to work that way. There aren't enough jobs for experienced, college educated managers and professionals.